JoAnn E. Manson is Professor of Medicine and the Elizabeth Fay Brigham Professor of Women’s Health at Harvard Medical School. She also is Professor in the Department of Epidemiology, Harvard School of Public Health, and Chief of the Division of Preventive Medicine and Co-Director of the Connors Center for Women’s Health and Gender Biology at Brigham and Women’s Hospital. An endocrinologist and epidemiologist, Dr. Manson is Principal Investigator of the large-scale VITamin D and OmegA-3 TriaL (VITAL), the Boston site of the Women’s Health Initiative (WHI) since its inception in 1993, the cardiovascular component of the Nurses’ Health Study, the WAFACS Trial, and the KEEPS Trial. She is actively involved with several large clinical trials and observational studies of cardiovascular disease and cancer. She has extensively studied the role of endogenous and exogenous hormones in relation to cardiovascular disease, diabetes, and other chronic diseases, the role of biochemical and genetic markers in predicting risk, and the effects of vitamin D and omega-3 fatty acids on health outcomes. She was a member of the Institute of Medicine Committee to Review Dietary Reference Intakes for Vitamin D and Calcium.